Resveratrol - Diabetes

 Resveratrol and Diabetes

RESVERATROL is a phytoalexin anti-oxidant that is produced from the skin of red grapes, Japanese knotweed root, and other plant sources. It is being hailed as the most promising nutritional discovery in modern times and it is being attributed to a host of beneficial health effects. For this reason, we dedicate this site to looking at the disease Diabetes and examine how resveratrol is being linked as a possible treatment to reducing the risk of diabetes.
Diabetes
Diabetes is an ailment that prevents the production of insulin in the body and is a disorder which occurs when blood sugar level increases and there is malfunction in the metabolism. Diabetes currently affects 285 million people worldwide of which approx 48 million live in Europe. Even though diabetes affects nearly 4% of the world’s population, many people know very little about the disease
There are 2 primary types of diabetes:
Type 1 diabetes occurs when your immune system destroys the beta cells in the pancreas that create insulin. As a result, the body makes very little or no insulin of its own. People with type 1 diabetes must take insulin daily. Type 1 diabetes is sometimes called juvenile diabetes or insulin-dependent diabetes.
Type 2 diabetes occurs when the pancreas does not make enough insulin, or the body cannot properly use the insulin it does create. Eventually, the pancreas may stop producing insulin altogether. Type 2 diabetes can affect people at any age. In both men and women, the more overweight an individual is, the greater the risk of developing type 2 diabetes
It may also occur due to lack of physical activity or exercise. Stress and obesity are the other causes of this disease. Glucose levels in blood increase due to stress and anxiety
Diabetes, early warning signs
Many of the signs of Type 1 and Type 2 diabetes are similar. In each case, there is too much glucose in the blood and not enough in the cells of your body. High glucose levels in Type I am due to a lack of insulin because the insulin producing cells have been destroyed. Type 2 diabetes occurs when the body's cells become resistant to insulin that is being produced. In both cases, your cells aren't getting the glucose they need, and your body will let you know by giving you some of the following signs and symptoms
• Frequent trips to the bathroom: Urinating becomes more frequent
• Unquenchable Thirst: constantly feel the need to drink more
• Losing Weight Without Trying: weight loss is not as noticeable in Type 2
• Weakness and Fatigue: feel tired and rundown
• Tingling or Numbness in Your Hands, Legs or Feet:
Resveratrol and Diabetes
Resveratrol activates sirtuins, a class of proteins that are thought to underlie many of the beneficial effects of calorie restriction. Previous studies in mice found that resveratrol did activate sirtuins in the brain of these mice which resulted in improving their high levels of blood sugar and insulin. Sirtuin activators are now being tested in humans as anti-diabetic compounds.
Sirtuins are expressed virtually everywhere throughout the body and until now, little has been known about what tissues mediate resveratrol's beneficial effects. Knowing where in the body the beneficial effects of activated sirtuins are mediated could help in the development of more effective targeted diabetes medications.
"We know that sirtuins are expressed in parts of the brain known to govern glucose metabolism, so we hypothesized that the brain could be mediating resveratrol's anti-diabetic actions," said Roberto Coppari, PhD, of the University of Texas South-western Medical Centre and co-author of the study. "To test the hypothesis, we assessed the metabolic consequences of delivering resveratrol directly into the brain of diabetic mice. We found that resveratrol did activate sirtuins in the brain of these mice which resulted in improving their high levels of blood sugar and insulin."

Other research suggests that resveratrol can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes. The elevated levels of glucose that circulate in the blood of patients with diabetes causes micro- and macro vascular complications by damaging mitochondria, the tiny power plants within cells responsible for generating energy. When they are damaged they can leak electrons and make highly damaging 'free radicals'. Complications that can result when this happen include nephropathy (kidney disease), heart disease and retinopathy (which if left untreated can lead to blindness).
Researchers now believe that resveratrol stops the damage by helping cells make protective enzymes to prevent the leakage of electrons and the production of toxic 'free radicals'.

Dr. Matt Whiteman, Principal Investigator and Senior Lecturer at the Institute of Biomedical and Clinical Science, Peninsula Medical School suggests that their research shows the link between high levels of glucose, its damaging effect on cell structure, and the ability of resveratrol of protect against and mend that damage."
He added: "Resveratrol or related compounds could be used to block the damaging effect of glucose which in turn might fight the often life threatening complications that accompany diabetes. It could well be the basis of effective diet-based therapies for the prevention of vascular damage caused by hyperglycaemia in the future."


How might you reduce the possibility of occurrence?
When you have diabetes, it is very important that you learn to care for yourself to control the amount of sugar in your blood. Keeping the amount of sugar in your blood as normal as possible is the best way to stay healthy. Because diabetes is a chronic condition, caring for yourself is every bit as important as the treatment you receive from your doctor and healthcare team. Ultimately, it is you who determines the state of your health.
Taking responsibility for it involves many choices, including what you eat and how frequently you exercise. It also involves testing your blood sugar to make sure your blood glucose stays within acceptable levels, an important factor in reducing your risk of serious diabetes-related complications
Having diabetes, you make important decisions every day about food. What you eat has a greater impact on your blood glucose than anything else you do.
Most food turns into sugar—or blood glucose—before entering the bloodstream. Insulin then helps blood glucose move from the bloodstream into your body’s cells—from your brain to your muscles—where it is used for energy. Without insulin to unlock those cells and let glucose in, your body does not get the nourishment it needs, and excess glucose stays in the bloodstream.
When you eat, you put fuel into your body. That is why your blood glucose rises after you eat and why many people with diabetes need to use insulin near mealtimes. The insulin moves the blood glucose from the bloodstream to the cells, where it can be used.
Planning what, when and how much you eat plays a key part in keeping your blood glucose levels in the range your healthcare professional has discussed and set for you.
Foods High In Sugar Food low in Sugar/sugar free
Sugar, glucose, glucose syrup, dextrose, sucrose, icing sugar Artificial sweeteners, e.g. Canderel Sweetex, Hermaseta
Sweet squash and fizzy drinks - e.g. Ribena, Lucozade Drinking Chocolate Sweet squash and fizzy drinks - e.g. Ribena, Lucozade Drinking Chocolate
All sweets, e.g. Chocolate, toffee, fudge, tablet, mints, chocolate covered and cream filled biscuits, marzipan Fruit, plain biscuits or scone, sugar-free chewing gum
Sugar-coated or honey coated breakfast cereal, e.g. Frosties, Sugar Puffs Unsweetened breakfast cereal e.g. porridge, Weetabix, Branflakes, Cornflakes, Rice Krispies
Sweet pudding e.g. crumble, tarts, tinned fruit in syrup Fresh or dried fruit, diet yoghurt, sugar-free jelly, tinned fruit in natural juice
Marmalade, jam, honey, syrup Reduced sugar marmalade

Fill up on fibre and starchy (carbohydrate) foods
• Starchy foods include whole grain breakfast cereals, potatoes, rice, pasta, chapattis and whole grain bread.
• Make these foods the main part of every meal
• Add lentils, beans, split peas or broth mix to home-made soups and stews.
Cut down on fried and fatty foods
• Eat less butter, margarine, oil, lard, dripping, cheese and fatty meats
• Choose low fat dairy products e.g., skimmed or semi-skimmed milk, low fat spreads or cheeses instead of the full fat versions.
• Remember low fat products still contain a lot of fat so don't be tempted to use twice as much!
• Cut fat off meat, take skin off chicken and have smaller helpings of meat, fish, eggs and cheese.
• Watch out for hidden fat - eat fewer pies, sausage rolls, cakes, crisps and biscuits
• Grill, poach, and boil microwave or oven bake food instead of frying.
• If you need to use oil in cooking, measure it out so as to use less. Go for 'unsaturated' oils such as olive oil, sunflower oil or corn oil.
Eat plenty of fruit and vegetables
• Aim to eat 2-3 servings of fruit each day
• Buy fresh fruit or fruit tinned in natural juice
• All fruit is good for you including bananas and small quantities of grapes or dried fruit
• Try to eat at least 2-3 servings of vegetables and/or salad every day
• Use fresh, frozen or tinned vegetables
Eat less salt
• Cut down salt gradually so that you can get used to the taste change. Adding herbs and spices instead can help.
• Use as little salt as possible in cooking. Try not to add more salt to your meal at the table.
• Cut down on processed foods such as tinned and packet foods, salty meats, crisps and salted nuts.
Treatment for Diabetes
Diabetes does not have a cure, but it is treatable. With the proper treatment plan, you can reduce or even prevent the complications related to diabetes. Common treatments for diabetes include insulin injections, oral medications, diet and exercise
Diabetes is a complicated disease. It can affect many areas of your body as well as many areas of your life. Treatments for both type 1 and type 2 diabetes can bring on many new challenges. What you eat, medications, testing your blood glucose, exercising...all these can play a role in successful management of diabetes.
• Good nutrition is a key element of managing diabetes. What, when, and how much you eat all influence your blood sugar.
• Oral medication there is a number of oral drugs that are used to manage most type 2 diabetes patients: sulfonylureas, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, meglitinides, and DPP-4 inhibitors. Each of these classes of drugs works in different ways to help maintain good glucose control
• Insulin is necessary when treating type 1diabetes. Type 1 diabetes occurs when the pancreas stops making insulin. People with type 1 need to inject insulin to keep their blood glucose from soaring out of control. Insulin is also used for type 2 diabetes, if oral medications are not enough to keep blood glucose levels in a normal range.

Purchase Resveratrol
If you would like to start taking resveratrol then please check out our products which can be purchased on our shop page. Our products are Trans Resveratrol which is the better grade of resveratrol. We have a range of purity levels and prices to meet your needs. 

 3 reasons to buy your resveratrol here
A. Best Prices for purity, grms per capsule size with no delivery charges
B. Real company based in Ireland manufacturing for European and U.S.A market
C. Great up to date information on resveratrol ,any questions talk to us.

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